Low Serum Allopregnanolone Is Associated with Symptoms of Depression in Late Pregnancy

Low serum allopregnanolone is associated with symptoms of depression in late pregnancy.

BACKGROUND Allopregnanolone (3α-hydroxy-5α-pregnan-20-one) is a neurosteroid which has an inhibitory function through interaction with the GABAA receptor. This progesterone metabolite has strong sedative and anxiolytic properties, and low endogenous levels have been associated with depressed mood. This study aimed to investigate whether the very high serum allopregnanolone levels in late pregna...

Is Life Expectancy Associated with Depression in the Elderly?

Introduction: Depression is one of the most common psychiatric disorders and risk factors for suicide in aging that often underdiagnosed and those who are more hopeful, suffer from less depression. The present study was conducted to determine the relationship between life expectancy and depression among older people in Yazd, Iran.   Methods: This descriptive cross-sectional study was con...

Maternal serum ferritin concentration is positively associated with newborn iron stores in women with low ferritin status in late pregnancy.

Iron deficiency (ID) is common in pregnant women and infants, particularly in developing countries. The relation between maternal and neonatal iron status remains unclear. This study considered the issue in a large sample of mother-newborn pairs in rural southeastern China. Hemoglobin (Hb) and serum ferritin (SF) were measured in 3702 pregnant women at ≥37 wk gestation and in cord blood of thei...

Pregnancy is associated with psychiatric symptoms in a low-income countryside community of Brazil

BACKGROUND Psychiatric symptoms during pregnancy induce an increase in morbidity and also in the mortality levels among women and children. However, the real association between pregnancy and psychiatric disorders and the peculiarities of the phenomenology of symptoms in underprivileged countryside communities remain uncertain. OBJECTIVE To verify the association between psychiatric disorder,...

Serum Level of Soluble CD226 Receptor in Healthy Individuals is Highly Variable and Associated with Age